Alkalosis

Causes

Appropriate Tests

 

Blood gas arterial, Electrolytes, Anion gap. See also Acidosis.

Metabolic alkalosis

Defined as alkalosis with a positive base excess and increased bicarbonate.

Volume (chloride) depletion, especially

  • Vomiting
  • Gastric drainage
  • Diuretic therapy

 

Adrenocortical hyperfunction, especially

  • Cushing's syndrome
  • Hyperaldosteronism

 

Severe potassium depletion

See under Hypokalaemia.

Excessive alkali intake

 

Compensatory

In primary respiratory acidosis.

Respiratory alkalosis

Defined as alkalosis with decreased pCO2.

Hyperventilation, especially

  • Functional
 
  • Salicylate poisoning

Salicylate.

  • Neurological disorders

 

Compensatory

In primary metabolic acidosis.