Anaemia of chronic disease

Keywords: Anaemia of inflammation, Anaemia of chronic disease (anaemia of inflammation)

Causes

Appropriate Tests
 
 
 

Chronic inflammation, chronic disease, eg, Rheumatoid arthritis, chronic infection

Full blood count, Blood film, C-Reactive protein, Erythrocyte sedimentation rate; Reticulocyte count; Iron studies, Soluble transferrin receptor.

Anaemia is normocytic or microcytic and is due to abnormal iron utilisation despite adequate bone marrow iron stores and a blunted erythropoietin response to anaemia.

Results of Ferritin may be difficult to interpret. See Table 3. Ratio of Soluble transferrin receptor/serum ferritin may be useful in some cases where Iron studies are ambiguous. A trial of iron supplementation may also be of value.

See also Anaemia.