Bullous skin lesions

Causes

Appropriate Tests

Solar/thermal injury

Diagnosis based on history and physical examination, with selected diagnostic imaging, endoscopy and pathology tests, as indicated.

Contactants, including

  • Rhus tree
  • Grevillea (Robyn Gordon type)
  • Poison ivy
  • Chemicals

Patch testing is sometimes indicated. It should only be performed by a specialist practitioner, as reactions may be severe.

Bullous impetigo

 

Herpes simplex virus infection

 

Varicella zoster infection

 

Pemphigus

Pemphigus Ab.

Pemphigoid

Pemphigoid Ab.

Erythema multiforme

 

Porphyria, especially

  • Porphyria cutanea tarda
  • Porphyria variegata

 

Porphyrins urine.
Porphyrins urine, Porphobilinogen urine, Porphyrins faeces.

SLE

 

Epidermolysis bullosa

Molecular genetics, if available.

Dermatitis herpetiformis

Transglutaminase Ab.

See also Coeliac disease.

Staphylococccal scalded skin syndrome

Clotted blood for TSST-1 analysis in specialist laboratory.

Toxic epidermal necrolysis

 

Graft versus host disease

 

Fixed drug reactions, especially

  • Tetracycline