Cyanosis

Causes

Appropriate Tests

 

Initial clinical assessment; pathology tests as appropriate.

Peripheral cyanosis

 

Reduced peripheral perfusion

 

Cold related disorders

 

  • Cardiac failure

 

  • Shock

 

Central cyanosis

Blood gas arterial, co-oximetry. Full blood count, Blood film.

Respiratory failure

 

Right to left shunts

 

  • Congenital heart disease

 

Methaemoglobinaemia

Methaemoglobin, Sulphaemoglobin. Heinz body preparation.
  • Nitrites

 

  • Sulphonamides

 

Haemoglobinopathy

 

  • Haemoglobin M

Identification of Haemoglobin M including Haemoglobin electrophoresis.

Further investigation - specialised laboratory.

Sulphaemoglobinaemia

See Methaemoglobinaemia, above.

  • Oxidant drugs