Fetal death

Causes

Appropriate Tests

 

A detailed autopsy may be required, including examination of the placenta.

Some causes may be recurrent; future reproductive management should be guided by the autopsy findings.

Intrauterine infection, including

  • Cytomegalovirus infection
  • Listeriosis

 

Chromosome abnormalities, especially

  • Turner syndrome
  • Triploidy

Cytogenetics - prenatal and fetal.

Intrauterine growth retardation, including

  • Placental insufficiency

 

See Phospholipid antibody syndrome.

Multiple gestation, especially

  • Twin-twin transfusion syndrome
  • Cord entanglement

 

Fetomaternal haemorrhage

Haemoglobin F - Kleihauer test.

Fetal haemolysis, including;

  • Hb Bart’s Hydrops fetalis
  • Haemolytic disease of the newborn

 

Molecular genetics - genetic disorders (Thalassaemia). See also Hydrops fetalis.

Fetal malformations

 

Haemangioma of cord or placenta

 

Amniotic bands

 

Maternal Diabetes mellitus

 

Reference

Fretts RC. Am J Obstet Gynecol 2005; 193: 1923-35.