Goitre

Key Information

Appropriate Tests

 

Clinical assessment, with Thyroid stimulating hormone and diagnostic imaging (if appropriate), to define nature of the thyroid swelling, indicate presence of Hyperthyroidism or Hypothyroidism.

Diffuse

Fine needle aspiration biopsy may be helpful when an inflammatory or neoplastic process is suspected.

'Physiological', especially

  • Adolescence
  • Pregnancy

 

Iodine deficiency

 

Thyroiditis, especially

  • Hashimoto thyroiditis
  • De Quervain's disease

 

Thyroid Ab. Erythrocyte sedimentation rate.

Graves' disease

See under Hyperthyroidism.

Lymphoma (non-Hodgkin)

See Lymphoma (non-Hodgkin)

Thyroid (anaplastic) carcinoma

 

Goitrogen exposure, especially

  • Iodides
  • Lithium

 

Brassica vegetables

 

Cassava

 

Biosynthetic defects

The presence of hypothyroidism should be detected on Neonatal screening (elevated Thyroid stimulating hormone levels).

Multinodular goitre

 

  • Non-toxic

 

  • Toxic

See Hyperthyroidism.

Solitary nodule

See Thyroid nodule/cyst.

Fine needle aspiration biopsy may be helpful when an inflammatory or neoplastic process is suspected.