Hepatitis B virus infection

Presentations

Appropriate Tests

 

Hepatitis B serology.

HBV viral load and genotyping may be indicated in certain clinical circumstances.

In vaccinated individuals, antibody to hepatitis B surface antigen (anti-HBs) can be used to confirm immunity.

Urinalysis; Bilirubin, Aspartate aminotransferase, Alanine aminotransferase, Alkaline phosphatase, Full blood count.

See also Hepatic failure, Hepatitis.

Acute hepatitis

 

Chronic carrier state

Defined as positive HBsAg for > 6 months. HBeAg for assessment of infectivity and risk of chronic liver disease.

Alpha-fetoprotein monitoring for detection of Hepatocellular carcinoma.

Chronic hepatitis

Liver biopsy may be indicated.

Chronic delta hepatitis

Hepatitis delta virus infection occurs only in patients with Hepatitis B infection.

See Hepatitis D virus infection.

Cirrhosis

 

Hepatocellular carcinoma

 

Glomerulonephritis

 

References

See also Pathology Decision Support Tool: Hepatitis B