Hodgkin lymphoma

Keywords: Hodgkin's lymphoma, Hodgkin's disease, Lymphoma

Key information

Appropriate Tests

 

Lymph node biopsy or tissue biopsy: excision biopsy preferred over fine needle aspiration biopsy, Full blood count, Blood film, Erythrocyte sedimentation rate, Bone marrow biopsy (aspiration and trephine).

See also Lymphoma (classification).

Presentation

 

Lymphadenopathy

 

Pyrexia of unknown origin

 

Weight loss

 

Pruritus

 

Classification

Histological findings and extent of disease (staging) are of importance in defining prognosis and determining appropriate management.

Review clinical features. Full blood count, Erythrocyte sedimentation rate; Bilirubin, Aspartate aminotransferase, Alanine aminotransferase, Alkaline phosphatase, Lactate dehydrogenase. Diagnostic imaging. Liver biopsy.

Nodular lymphocyte predominant Hodgkin lymphoma

 

Classical Hodgkin lymphoma

 

  • Nodular sclerosis classical Hodgkin lymphoma
  • Lymphocyte-rich classical Hodgkin lymphoma
  • Mixed cellularity classical Hodgkin lymphoma
  • Lymphocyte-depleted classical Hodgkin lymphoma