Hyperaldosteronism

Keywords: Conn's syndrome

Key Information

Appropriate Tests

 

Patients usually present with hypertension and/or muscle weakness.

Electrolytes (hypokalaemia is usual, but a normal potassium does not exclude the diagnosis); Aldosterone / Renin ratio, Electrolytes urine.

If Aldosterone or aldosterone/renin ratio elevated, special studies are required - consult pathologist.

Primary

Hyporeninaemic hyperaldosteronism (Conn's syndrome).

Adrenal aldosterone secreting tumour (aldosteronoma)

 

Bilateral adrenal hyperplasia

 

Glucocorticoid suppressible

Aldosterone after 2 mg dexamethasone daily for 3 days.

Secondary

Hyperreninaemic hyperaldosteronism.

Renal disease, especially

 

  • Renovascular

Bilateral renal vein Renin; Renin after captopril load.

  • Bartter’s syndrome

Not associated with hypertension.

  • Renal haemangiopericytoma