Leukaemoid reaction

Causes

Appropriate Tests

 

Extreme peripheral blood leucocytosis (usually >50x 10^9/L), often with immature white cells, and a superficial resemblance to leukaemia.

Review clinical features, Full blood count, Blood film, White cell count differential; consult haematpathologist.

See also Table 4, Neutrophilia, Neutrophilia with early myeloid cells (Blood film)

Myeloid reaction

 

Carcinoma, especially advanced and/or metastatic

 

Severe/chronic often bacterial infection

  • Abscess
  • Tuberculosis

 

Cytokine therapy, especially G-CSF

 

Recovery from bone marrow aplasia/hypoplasia

 

Lymphoid reaction

 

Pertussis

 

Infectious mononucleosis