Lymphocytopenia

Keywords: Lymphopenia

Causes

Appropriate Tests

 

Review clinical findings, Full blood count, White cell count differential, Blood film.

Depending on the clinical context, a cause for mild isolated lymphopenia may not be apparent and may not require exhaustive investigation.

See Table 4.

Acute stress

 

Bacterial infection

 

Early stage of viral infection

 

Carcinoma, especially advanced disease.

 

Irradiation

 

Drugs, especially

  • Corticosteroids
  • Cytotoxic drugs

 

HIV infection

 

Hodgkin lymphoma

 

Malnutrition / Anorexia nervosa

 

Renal failure; acute and chronic.

 

SLE / RA

 

Cushing's syndrome; administration of corticosteroids

 

Sarcoidosis

 

Protein-losing enteropathy