Monocytosis

Key Information

Appropriate Tests

 

Review clinical findings. Full blood count, Blood film, White cell count differential.

See Table 4.

With monocytes showing normal morphology

 

Acute or chronic bacterial infection, especially

  • Tuberculosis

 

Carcinoma

 

Hodgkin lymphoma

 

Recovery from agranulocytosis

See Neutropenia

Cytokine administration

Cytokines (eg, G-CSF, GM-CSF) commonly cause Neutrophilia and/or Monocytosis.

Chronic idiopathic neutropenia

 

Splenic atrophy/absence

 

With abnormal 'monocytoid' cells

 

Myelodysplasia, especially

  • Chronic myelomonocytic leukaemia

Monocyte morphology may be abnormal.

Acute myelomonocytic, monocytic leukaemia

See Acute leukaemia.