Myocarditis

Causes

Appropriate Tests

 

Full blood count, White cell count differential, Blood film; C-Reactive protein or Erythrocyte sedimentation rate; Creatine kinase (CK) and CKMB; cardiac Troponin I and cardiac Troponin T are more sensitive and specific.

If diagnosis is uncertain or if confirmation is required: Myocardial biopsy including viral detection and bacterial culture.

Infection

 

Viral

Serology as indicated. Virus detection, culture- Throat swab / gargle and faeces.

  • Coxsackievirus B or A infection
  • Cytomegalovirus infection
  • HIV infection
  • Infectious mononucleosis
  • Influenza
  • Adenovirus infection

Definitive diagnosis usually requires virus detection, culture: enterovirus (coxsackievirus) antibodies are of little value.



 

Adenovirus Ab.

Bacterial associated

  • Diphtheria
  • Rheumatic fever
  • Lyme disease

 

Protozoal

  • Trypanosoma cruzii
  • Toxoplasmosis

 

See Chagas' disease under Trypanosomiasis

Other

  • Mycoplasma pneumoniae
  • Chlamydia psittaci

 

See Mycoplasma infection
Chlamydia Ab.

  • Q fever

Q Fever Ab.

Autoimmune

 

SLE

 

Vasculitis, especially

  • Polyarteritis nodosa

 

Drug effects, especially

  • Adriamycin
  • Daunorubicin

 

Other

 

Phaeochromocytoma

 

Idiopathic