Oral ulcers

Keywords: Stomatitis

Causes

Appropriate Tests

 

Clinical presentation and appearance of the ulcer(s) often suggest the diagnosis.

Pathology tests (including Full blood count ) are usually only indicated for severe, indolent or recurrent ulcers.

Aphthous ulcers

 

Traumatic ulcers

 

Infection, especially

 

  • Herpes simplex infection

 

  • Varicella zoster infection

 

  • Herpangina

Enterovirus Ab (coxsackievirus) are not useful.

  • Vincent's stomatitis

See Vincent's infection

  • HIV infection

 

  • Candidiasis

 

  • Syphilis

 

Neoplasia

Any solitary ulcer persisting for more than 3 weeks should be biopsied.

  • Carcinoma

 

Neutropenia

 

Systemic disorders, especially

 

  • Inflammatory bowel disease

 

  • Coeliac disease

 

  • SLE

 

  • Behçet's syndrome

 

  • Erythema multiforme

 

  • Pemphigus

Lesion biopsy with IF. Pemphigus Ab and Pemphigoid Ab.

  • Pemphigoid