Osteomyelitis

Causes

Appropriate Tests

 

Blood culture, MCS pus (collected at intra-operative drainage procedure or by aspiration), Wound swab microscopy and culture if contiguous skin lesion present, Bone biopsy.

Full blood count, Blood film, White cell count differential; C-Reactive protein.

Bacterial infection

 

Staphylococcus aureus
Coagulase negative staph and skin organisms (prosthetic infections)

 

Gram-negative bacilli

 

Aerobes

 

  • Haemophilus influenzae

In children: see Haemophilus influenzae infection.

  • Escherichia coli

 

  • Pseudomonas aeruginosa

 

  • Salmonella sp

 

Anaerobes

 

  • Bacteroides fragilis

 

Mycobacterium tuberculosis

Pus, Bone biopsy (including Fine needle aspiration biopsy) , Mycobacteria testing.

See also Tuberculosis.