Pigmentation (skin)

Keywords: Skin pigmentation

Causes Appropriate Tests

Localised

 

Sunlight/ultraviolet exposure

  • Chloasma, especially
    • Oral contraceptive use
See also Photosensitivity (skin)

Pigmented lesions

  • Naevi
  • Melanoma
  • Basal cell carcinoma
  • Seborrhoeic keratoses
  • Café au lait spots
  • Tinea versicolor

Clinical assessment; Skin biopsy.

 

 

See Neurofibromatosis
Skin scraping for MCS fungal (microscopy and culture).

Generalised

 

Metabolic, especially

  • Renal failure - chronic
  • Hereditary haemochromatosis
  • Haemosiderosis
  • Porphyria (except acute intermittent porphyria)
 

Endocrine, especially

  • Pregnancy
  • Addison's disease
  • Nelson's disease

 


See under Adrenocortical insufficiency
ACTH

Drug reactions, especially

  • Busulphan
  • Bleomycin
  • Oral contraceptives
  • Amiodarone