Rheumatoid arthritis

Key Information

Appropriate Tests

 

The diagnosis is made by clinical assessment of a polyarthritis persisting for more than 12 weeks and imaging. Full blood count, C-Reactive protein, Erythrocyte sedimentation rate to confirm the diagnosis of inflammatory arthritis.

A positive Rheumatoid factor and Cyclic citrullinated peptide Ab contributes to the diagnosis. 

Antinuclear Ab, Creatinine, Liver function tests, Urate, Parvovirus, Barmah forest virus, Ross River virus serology.

See also Rheumatoid arthritis (juvenile)

Extra-articular manifestations

 

Rheumatoid nodules

 

Anaemia of chronic disease

 

Neuropathy

 

Pleural effusion

 

Interstitial lung disease

 

Sjögren syndrome

 

Vasculitis

Complement components C3 and C4

Pericarditis

 

Felty syndrome

Lymphocyte surface markers.

Amyloidosis

 

Treatment-related complications

 

Anaemia

See also Anaemia of chronic disease

  • Iron deficiency, especially
    • NSAID therapy

Iron studies

  • Haemolysis, especially
    • Salicylazosulphapyridine

Glucose-6-phosphate dehydrogenase

  • Marrow suppression, especially
    • Gold
    • Methotrexate

See Pancytopenia

Pneumonitis, especially

  • Methotrexate

See Interstitial lung disease

Nephropathy, especially

  • Gold
  • NSAID

See Renal failure

Analgesic abuse

Renal tubulo-interstitial disorders

Hepatitis, especially

  • Methotrexate

See Hepatitis