Septicaemia

Key Information

Appropriate Tests

 

Blood culture x2.

Microbiological studies, as appropriate, on any identified focus of infection.

MCS urine.

Full blood count, Blood film, White cell count differential, Platelet count; Electrolytes, Creatinine, Urea, Liver function tests, Coagulation profile, Calcium, Phosphate, Albumin. Consider Troponin, Lipase, Beta HCG quantitation in females, Lactate, Blood group and hold, Blood gas arterial.

Antimicrobial treatment should not be delayed if the patient is clinically septicaemic.

In severely ill patients: Blood gas arterial, Lactate, C-Reactive protein.

See Guideline on Pathology testing in the Emergency department: Appendix 2.

Presentations

 

Shock

 

DIC

 

Respiratory distress syndrome

 

Renal failure - acute

 

Predisposing factors

 

Intravenous cannula

Culture of cannula tip and wound swab of cannula site.

Urinary tract instrumentation

MCS urine - Urine microscopy and culture.

Abscess

 

Intravenous drug abuse

 

Neutropenia

See also Febrile neutropenia.

Immunodeficiency, especially

  • HIV infection
  • Post-splenectomy

See also Infection (increased susceptibility)

See Splenic atrophy/absence