Glossary

5-HT - Serotonin

AAT - Alpha-1-antitrypsin

Ab - Antibody

ACD - Acid citrate dextrose

ACE - Angiotensin converting enzyme

Acetylcholine receptor Ab - Acetylcholine receptor antibody

ACT - Activated clotting time

Adenovirus Ab - Adenovirus antibody

ADH - Antidiuretic hormone

ADP - Adenosine diphosphate

Adrenal Ab - Adrenal antibody

AFB - Acid fast bacilli

AFP - Alpha-fetoprotein

Ag - Antigen

AIDS - Acquired immunodeficiency syndrome

ALA - Aminolaevulinate

ALL - Acute lymphoblastic leukaemia

ALP - Alkaline phosphatase

ALT - Alanine aminotransferase

AML - Acute myeloid leukemia

AMP - Adenosine monophosphate

ANA - Antinuclear antibody

ANCA - Antineutrophil cytoplasmic antibody

Anti Immunoglobin A Ab - Anti Immunoglobin A antibody

Anti phospholipase A2 receptor 1 Ab - Anti phospholipase A2 receptor 1 antibody

Anti-HBc - Antibody to hepatitis B core antigen

Anti-HBe - Antibody to hepatitis B e antigen

Anti-HBs - Antibody to hepatitis B surface antigen

Anti-HCV - Antibody to hepatitis C virus

APC - APC resistance

APTT - Activated partial thromboplastin time

Arbovirus Ab - Arbovirus antibody

ASOT - Antistreptolysin O titre

AST - Aspartate aminotransferase

BCG - Bacillus Calmette-Guerin

B-HCG - Beta HCG, Beta HCG quantitation

BNP - B-type natriuretic peptide

Bordetella pertussis Ab - Bordetella pertussis antibody

Borrelia burgdorferi Ab - Borrelia burgdorferi antibody

Brucella Ab - Brucella antibody

Burkholderia pseudomallei Ab - Burkholderia pseudomallei antibody

C1 - First component of complement

C3 - Third component of complement

C4 - Fourth component of complement

Ca - Calcium

Carcinoembryonic Ag - Carcinoembryonic antigen

Cardiolipin Ab - Cardiolipin antibody

Cat scratch disease Ab - Cat scratch disease antibody

CBA - Collagen binding assay

CD - Cluster of differentiation

CDC - Centers for Disease Control Prevention

CEA - Carcinoembryonic antigen

Centromere Ab - Centromere antibody

CFT - Complement fixation test

CGD - Chronic granulomatous disease

CH50/CH100 - Total haemolytic complement activity

Chlamydia Ab - Chlamydia antibody

Chlamydia pneumoniae Ab - Chlamydia pneumoniae antibody

CIE - Counter immunoelectrophoresis

CJD - Creutzfeldt Jakob disease

CK - Creatine kinase

CKMB - Creatine kinase MB isoenzyme

CLL - Chronic lymphocytic leukaemia

CML - Chronic myeloid leukaemia

CMML - Chronic myelomonocytic leukaemia

CMV - Cytomegalovirus

CNS - Central nervous system

ConA - Concanavalin A

COPD - Chronic obstructive pulmonary disease

CREST - Calcinosis, Reynaud's phenomenon, oseophageal hypomotility, sclerodactyly, telangiectases

CREST syndrome (limited scleroderma) - Calcinosis, Reynaud's phenomenon, oseophageal hypomotility, sclerodactyly, telangiectases syndrome (limited scleroderma)

CRP - C-Reactive protein

Cryptococcal Ag - Cryptococcal antigen

CSF - Cerebrospinal fluid

CVS - Chorionic villus sampling

Cytomegalovirus Ab - Cytomegalovirus antibody

DDAVP - Desmopressin acetate; 1-desamino-8-D-arginine vasopressin

Deaminated gliadin Ab - Deaminated gliadin antibody

DFA - Direct fluorescent antibody technique

DHEAS - DHEA sulphate

DIC - Disseminated intravascular coagulation

DNA - Deoxyribonucleic acid

Donath-Landsteiner Ab - Donath-Landsteiner antibody

EBNA - Epstein Barr nuclear antigen

EBV - Epstein Barr virus

ECP - Eosinophil cationic protein

EDTA - Ethylene diamine tetra-acetic acid

eGFR - Estimated glomerular filtration rate

EIA - Enzyme immunoassay

EM - Electron microscopy

ENA - Extractable nuclear antigen antibody

Endomysial Ab - Endomysial antibody

Endomysial Ab IgA - Endomysial antibody IgA

Entamoeba Ab - Entamoeba antibody

Enterovirus Ab - Enterovirus antibody

EPG - Electrophoretogram (electrophoresis)

EPO - Erythropoietin

EPX - Eosinophil protein X

ESR - Erythrocyte sedimentation rate

Extractable nuclear antigen Ab - Extractable nuclear antigen antibody

FAB - French-American-British

Fasciola hepatica Ab - Fasciola hepatica antibody

FBC - Full blood count

FDP - Fibrin/fibrinogen degradation products

Filaria Ab - Filaria antibody

FiO2 - Fractional concentration of inspired oxygen

FISH - Fluorescence in situ hybridisation

FITC - Fluorescein isothiocyanate

FNAB - Fine needle aspiration biopsy

FS - Frozen section

FSH - Follicle stimulating hormone

FT3 - Free T3

FT4 - Free T4

FTA-ABS - Fluorescent treponemal antibody absorption test

G-6-PD - Glucose-6-phosphate dehydrogenase

G-6-PD deficiency - Glucose-6-phosphate dehydrogenase deficiency

GC - Gas chromatography

GCMS - Gas chromatography mass spectrometry

G-CSF - Granulocyte colony stimulating factor

GGT - Gamma glutamyltransferase

GLC - Gas liquid chromatography

Gliadin Ab - Gliadin antibody

GLL - Granular lymphocytic leukaemia

Glomerular basement membrane Ab - Glomerular basement membrane antibody

GM-CSF - Granulocyte macrophage colony stimulating factor

GN - Glomerulonephritis

GST - Glutathione s-transferase

GTT - Glucose tolerance test

HAI - Haemagglutination inhibition

HAV - Hepatitis A virus

Hb - Haemoglobin

HbA2 - Haemoglobin A2

HBeAg - Hepatitis B e antigen

HbF - Haemoglobin F

HbH - Haemoglobin H

HbM - Haemoglobin M

HbS - Haemoglobin S

HBsAg - Hepatitis B surface antigen

HBV - Hepatitis B virus

HBV DNA-p - Hepatitis B virus DNA polymerase

hCG - Human chorionic gonadotrophin

HCl - Hydrochloric acid

HCO3 - Bicarbonate

Hct - Haematocrit

HCV - Hepatitis C virus

HDL - High-density lipoprotein cholesterol

HDV - Hepatitis D virus

Heat shock protein 70 Ab - Heat shock protein 70 antibody

Helicobacter pylori Ab - Helicobacter pylori antibody

HEMPAS - Hereditary erythroblast multinuclearity with positive acidified serum test

Hendra virus Ab - Hendra virus antibody

Hepatitis A total Ab - Hepatitis A total antibody

Hepatitis D Ab - Hepatitis D antibody

Hepatitis E Ab - Hepatitis E antibody

HER-2 - Human epidermal growth factor receptor 2

Herpes simplex Ab - Herpes simplex antibody

HEV - Hepatitis E virus

hGH - Human growth hormone

HGV - Hepatitis G virus

HIAA - 5HIAA urine

Histone Ab - Histone antibody

HIT - Heparin-induced thrombocytopenia

HIV - Human immunodeficiency virus

HIV Ab and Ag combination - HIV antibody and antigen combination

HLA - Human leucocyte antigen

HMGCoA - 3-Hydroxy-3-methylglutaryl coenzyme A

HMMA - 4-hydroxy-3-methoxymandelate

HOCM - Hypertrophic obstructive cardiomyopathy

HPLC - High performance liquid chromatography

HPV - Human papillomavirus

HSV - Herpes simplex virus

HTLV - Human T cell lymphotropic virus

HTLV Ab - HTLV antibody

HVA - Homovanillic acid urine

Hydatid Ab - Hydatid antibody

HZV - Herpes zoster virus, Varicella zoster

ICCS - Intercellular cement substance

ID - Immunodiffusion

IDDM - Insulin dependent diabetes mellitus

IDL - Intermediate density lipoprotein

IEF - Isoelectric focussing

IEP - Immunoelectrophoresis

IF - Immunofluorescence

IFA - Indirect fluorescent antibody technique

IFA - Intrinsic factor Ab

IFE - Immunofixation electrophoresis

Ig - Immunoglobulin

IgE - Immunoglobulin E total

IGF - Insulin-like growth factor

IH - Immunohistology

IHA - Indirect haemagglutination

IM - Infectious mononucleosis

IMI - Intramuscular injection

Influenza Ab - Influenza antibody

Influenza Ag - Influenza antigen

INR - International normalised ratio

Intrinsic factor Ab - Intrinsic factor antibody

ISE - Ion selective electrode

ITP - Immune thrombocytopenic purpura

IV - Intravenous

Jo-1 Ab - Jo-1 antibody

K - Potassium

kg - Kilogram

kPa - Kilopascal

LA - Latex agglutination

LC-MS - Liquid chromatography–mass spectrometry

LC-MS/MS - Liquid chromatography–mass spectrometry

LD - Lactate dehydrogenase

LDH - Lactate dehydrogenase

LDL - Low-density lipoprotein cholesterol

Legionella Ab - Legionella antibody

Legionella Ag - Legionella antigen

Legionella pneumophila serogroup 1 Ag - Legionella pneumophila serogroup 1 antigen

Leptospiral Ab - Leptospiral antibody

LFT - Liver function tests

LGV - Lymphogranuloma venereum

LH - Luteinising hormone

Liver/kidney microsome Ab - Liver/kidney microsome antibody

LKM - Liver/kidney microsome antibody

LM - Light microscopy

LMWH - Low molecular weight heparin

Lymphocytotoxic Ab - Lymphocytotoxic antibody

MAIPA - Monoclonal antibody immobilisation of platelet antigen

Malaria Ag - Malaria antigen

MBC - Minimum bactericidal concentration

MCF - Median corpuscular fragility

MCH - Mean cell haemoglobin

MCHC - Mean cell haemoglobin concentration

MCV - Mean cell volume

MDS - Myelodysplastic syndromes (classification)

Measles virus Ab - Measles virus antibody

MEN - Multiple endocrine neoplasia

MEN2 - Multiple endocrine neoplasia type 2

MGUS - Monoclonal gammopathy of unknown significance

MHMA - 3-methoxy-4-hydroxymandelate

MIC - MIC susceptibility

Mitochondrial Ab - Mitochondrial antibody

MOM - Multiples of median

MSA - Mammary specific antigen

Mumps Ab - Mumps antibody

Muscle specific receptor tyrosine kinase Ab - Muscle specific receptor tyrosine kinase antibody

Mycobacterium tuberculosis IGRA - Mycobacterium tuberculosis interferon-gamma release assays

Mycoplasma pneumoniae Ab - Mycoplasma pneumoniae antibody

Myelin Ab - Myelin antibody

Myeloperoxidase Ab - Myeloperoxidase antibody

Myocardial Ab - Myocardial antibody

Na - Sodium

NADPH - Nicotinamide adenine dinucleotide phosphate

NAP - Neutrophil alkaline phosphatase

Neuromyelitis optica Ab - Neuromyelitis optica antibody

Neuronal Ab - Neuronal antibody

Neutrophil Ab - Neutrophil antibody

NK - Natural killer cells

NMDA receptor Ab - NMDA receptor antibody

NSAID - Nonsteroidal anti-inflammatory drugs

NSE - Neuron-specific enolase

NT-BNP - N-terminal B-type natriuretic peptide

Ovarian Ab - Ovarian antibody

p50 O2 - Partial pressure of O2 at which haemoglobin is 50% saturated

PAI - Plasminogen activator inhibitor

PAN - Polyarteritis nodosa

Parathyroid Ab - Parathyroid antibody

Parietal cell Ab - Parietal cell antibody

Parvovirus B19 Ab - Parvovirus B19 antibody

PBC - Primary biliary cirrhosis

PCI - Prothrombin consumption index

PCR - Polymerase chain reaction

PCV - Packed cell volume, Haematocrit

Pemphigus Ab - Pemphigus antibody

PF3 - Platelet factor 3

PHA - Phytohaemagglutinin

PID - Pelvic inflammatory disease

PIE - Pulmonary infiltration with eosinophilia

PKU - Phenylketonuria

Platelet Ab - Platelet antibody

PNH - Paroxysmal nocturnal haemoglobinuria

PPD - Purified protein derivative

PR - Prothrombin ratio

Proteinase3 Ab - Proteinase3 antibody

PRV - Polycythaemia rubra vera

PRV+MRD - Polycythaemia rubra vera + minimal residual disease

PSA - Prostate specific antigen

PT - Prothrombin time

PTH - Parathyroid hormone

PTHrP - Parathyroid hormone related protein

PUO - Pyrexia of unknown origin

Q Fever Ab - Q Fever antibody

Rabies virus Ab - Rabies virus antibody

RAST - Radioallergosorbent test

RCC - Red cell count

RCoF - Ristocetin cofactor

RDS - Respiratory distress syndrome

RDW - Red cell distribution width

REAL - Revised European-American lymphoma classification

Respiratory syncytial virus Ag - Respiratory syncytial virus antigen

RF - Rheumatoid factor

RFLP - Restriction fragment length polymorphism

Rh - Rhesus (blood group)

RIA - Radioimmunoassay

Rickettsial Ab - Rickettsial antibody

RNA - Ribonucleic acid

RPR - Rapid plasma reagin test

RSV - Respiratory syncytial virus Ag

Rubella Ab - Rubella antibody

SARS - Severe acute respiratory syndrome

SBE - Subacute bacterial endocarditis

SCA - Spino-cerebellar ataxias

Schistosomiasis Ab - Schistosomiasis antibody

SCID - Severe combined immunodeficiency

SDS - Sodium dodecyl sulphate

SHBG - Sex hormone binding globulin

SIADH - Syndrome of inappropriate antidiuretic hormone secretion

SIDS - Sudden infant death syndrome

Skeletal muscle Ab - Skeletal muscle antibody

SLE - Systemic lupus erythematosus

Smooth muscle Ab - Smooth muscle antibody

sp - Species

Sperm Ab - Sperm antibody

SSPE - Subacute sclerosing panencephalitis

STD - Sexually transmitted diseases

Streptococcus pneumoniae Ag - Streptococcus pneumoniae antigen

Strongyloides sp Ab - Strongyloides sp antibody

T3 - Triiodothyronine

T4 - Thyroxine (tetraiodothyronine)

Taenia solium Ab - Taenia solium antibody

TBG - Thyroxine binding globulin

Testicular Ab - Testicular antibody

TGFβ - Transforming growth factor beta

Thyroid Ab - Thyroid antibody

TIBC - Iron / Iron binding capacity

TLC - Thin layer chromatography

TNF - Tumour necrosis factor

TORCH - Toxoplasmosis, other infections, rubella, cytomegalovirus, herpes simplex

Toxocara Ab - Toxocara antibody

Toxoplasma Ab - Toxoplasma antibody

TPHA - Treponema pallidum haemagglutination

TPI - Treponema pallidum immobilisation

Transglutaminase Ab - Transglutaminase antibody

TRH - Thyrotropin releasing hormone

Trypanosome Ab - Trypanosome antibody

TSH - Thyroid stimulating hormone

TSH receptor Ab - TSH receptor antibody

TTP - Thrombotic thrombocytopenic purpura

Typhoid Ab - Typhoid antibody

var - Variety

Varicella zoster Ab - Varicella zoster anitbody

VCA - Viral capsid antigen (EBV)

VDRL - Venereal Disease Research Laboratory test

VIP - Vasoactive intestinal polypeptide

VLDL - Very low density lipoprotein

Voltage gated potassium channel Ab - Voltage gated potassium channel antibody

von Willebrand factor Ag - von Willebrand factor antigen

VWD - von Willebrand disease

vWf - von Willebrand factor

vWfAg - von Willebrand factor antigen

WAGR - Wilms tumour, aniridia, genitourinary anomalies, and mental retardation

WCC - White cell count

XDP - Cross linked fibrin degradation products

Yersinia sp Ab - Yersinia sp antibody

MCS - Microscopy culture sensitivities

FBE - Full blood examination

FMH - feto-maternal haemorrhage