Arsenic urine

Keywords: Urine arsenic, Urine As

Specimen:

Acute poisoning: random urine specimen.

Chronic poisoning: 24 h urine collection with acid preservative.

Occupational exposure: collection at the end of a shift at the end of the working week. Fish and shellfish must be excluded from the diet for one day, and seaweed for three days, as they may contain high levels of non-toxic organic arsenicals.

Method:

Inductively coupled plasma mass spectrometry (ICP-MS).

Reference Interval:

< 3 µmol/24 h.

Application:

Suspected arsenic poisoning.

Interpretation:

> 13 μmol/24 h indicates toxicity.

Reference:

Robson M. Ecotoxicol Environ Saf  2003; 56: 104-109.