Heat shock protein 70 Ab

Keywords: Heat shock protein 70 antibody

Specimen:

5 mL blood in plain tube.

Method:

Western blot.

Reference Interval:

Consult pathologist.

Application:

Of limited value in delineating a group of patients with idiopathic progressive bilateral sensorineural hearing loss who may be responsive to immunosuppressive therapy.

Interpretation:

Between 20-70% of patients with idiopathic sensorineural hearing loss will be positive for this antibody.

Approximately 30% of patients with Meniere's disease will also be positive.

Reference:

Billings PB. Ann Otol Rhinol Laryngol. 1995; 104: 181-188.