Liver/kidney microsome Ab

Keywords: Liver/kidney microsome antibody, LKM antibody

Specimen:

5 mL blood in plain tube.

Method:

IF and line blot.

Reference Interval:

Consult laboratory.

Application:

Assessment of chronic hepatitis.

Interpretation:

A positive result is present in a sub-group of autoimmune hepatitis associated with a poorer prognosis than the more common form of autoimmune hepatitis, with positive Smooth muscle Ab.

A positive result may also be seen in Hepatitis C virus infection.

Reference:

Manns M.P. In: Schiff E et al. Schiff’s Diseases of the liver. 8th Ed Vol 2. 1999. Lippincott-Raven.