Myelin Ab

Keywords: Myelin antibody

Specimen:

5 mL blood in plain tube.

Method:

Immunoassay (EIA). Myelin basic protein.

Application:

No proven clinical utility, largely superseded by antibodies to myelin glycolipids of uncertain role in diagnosis/follow up of multiple sclerosis.

Application of possible role identification of neuropathies in IgM monoclonal gammopathy.

Interpretation:

The frequency of myelin antibodies in patients with peripheral neuropathy is essentially identical to that found in normal individuals.

Reference:

Berger, T et al. Journal of Neural Transmission. Supplementary. 2000; 60: 351-360.