Oestradiol

Keywords: E2, Estradiol

Specimen:

5 mL blood in plain tube

Method:

Immunoassay, LC-MS/MS.

Reference Interval:

Female:

Early follicular phase: 100-200 pmol/L

Preovulatory phase: 500-1700 pmol/L

Luteal phase: 500-900 pmol/L

Postmenopausal: 70-200 pmol/L.

Application:

Diagnosis of precocious puberty.

Monitoring of oestrogen therapy is only possible if the drug being administered is oestradiol.

Monitoring ovulation induction in in vitro fertilisation.

Assessment of women with suspected hypothalamic or pituitary disease.

Interpretation:

Increased levels indicate an endogenous or exogenous source of increased oestradiol.

Reference:

Goldfien A and Monroe SE. In: Greenspan FS and Baxter JD eds. Basic and Clinical Endocrinology. 4th ed. 1994. Prentice Hall.