Pancreatic elastase faeces

Description:

See Trypsin faeces and Chymotrypsin faeces.

Specimen:

5 g faeces (random) frozen immediately after collection.

Method:

Immunoassay.

Reference Interval:

Normal > 200 µg/g.

Application:

Diagnosis of pancreatic exocrine failure.

Interpretation:

Faecal elastase is reduced in pancreatic exocrine failure.

Malabsorption is not usually obvious until > 95% of the pancreas has been destroyed.

Values of 100-200 µg/g indicate moderate, and < 100 µg/g severe, pancreatic insufficiency.

Reference:

Sonwalkar SA et al. Aliment Pharmacol Ther 2003; 17(3): 467-471.