Pemphigus Ab

Keywords: Pemphigus antibody

Specimen:

10 mL blood in plain tube.

Method:

Indirect IF, Immunoassay.

Reference Interval:

Method dependent.

Application:

Diagnosis of bullous skin diseases.

Differentiates pemphigus from pemphigoid.

Interpretation:

Intercellular cement substance antibodies (also known as desmoglein antibodies) are specific for pemphigus.

Titres correlate with disease activity and effect of treatment.

Pemphigus-like antibodies occur in burns, drug reactions and other disorders with extensive skin damage.

Reference:

Stanley J. J Exp Med. 1995; 181: 1-4.

Zagorodniuk I. et al. International Journal of Dermatology. 2003; 44(7) 541 - 544