pH urine

Specimen:

Freshly voided, random urine specimen without preservative.

Method:

Hydrogen ion electrode or reagent strip.

See also Urinalysis.

Reference Interval:

Physiological range is 4.5-8.0.

Application:

Investigation of renal tubular acidosis and monitoring urine pH for other reasons (eg, alkali therapy in cystinuria).

Interpretation:

In general, urine pH reflects the pH of the blood.

In distal renal tubular acidosis the urine pH is > 5.3 during metabolic acidosis, whereas in normals, or in patients with proximal renal tubular acidosis, urine pH is < 5.3 during metabolic acidosis.

Acid urine is produced in metabolic alkalosis with potassium depletion, eg, in pyloric stenosis.

Reference:

Roth KS et al. Clin Pediatr. 2001; 40(10): 533-543.