Skeletal muscle Ab

Keywords: Skeletal muscle antibody

Specimen:

5 mL blood in plain tube.

Method:

Indirect IF.

Reference Interval:

Not detected.

Application:

Assessment of patients with documented myasthenia gravis; detected in 40% of affected subjects, but in over 90% of those with thymoma.

Acetylcholine receptor antibodies should also be requested.

Interpretation:

A positive result indicates that the possibility of thymoma should be actively investigated.

Reference:

Skeie G. Annals of the New York Academy of Science. 2003; 998: 343-350.