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Inflammation and Infection

Inflammatory cells, blood and debris

Inflammatory cells, blood cells and debris may be reduced by the preparation of LBC slides however their presence is still demonstrated.

ThinPrep® - Inflammation

ThinPrep® - Inflammation

Numerous polymorphonuclear leucocytes are evident in this TP preparation, indicating the presence of a marked inflammatory exudate.

SurePath™ - Inflammation

SurePath™ - Inflammation

A marked inflammatory exudate is represented in this SP preparation.
 

ThinPrep® - Red blood cells

ThinPrep®  - Red blood cells

Red blood cells lysed during slide preparation appear as pale staining fragments.

 

SurePath™ - Old blood

SurePath™ - Old blood

Blood is largely removed from SP slides during preparation however degenerate blood may occasionally be seen, as in this preparation with accompanying tumour cells.

Trichomonas, Candida, Actinomyces, Herpes

Microorganisms may be more clearly seen in LBC slides however their presentation may vary slightly from that seen in CP.

ThinPrep® - Trichomonas

ThinPrep®  - Trichomonas

Trichomonas appear slightly larger than polymorphonuclear leucocytes and display elongated nuclei.

SurePath™ - Trichomonas

SurePath™ - Trichomonas

Trichomonas displaying small elongated nuclei with accompanying inflammatory cells.
 

ThinPrep® - Candida

ThinPrep®  - Candida

Candida showing clearly defined pseudohyphae with associated clumping of squamous epithelial cells

SurePath™ - Candida

SurePath™ - Candida

Clearly defined pseudohyphae with trapped epithelial cells.
 

ThinPrep® - Herpes virus

ThinPrep®  - Herpes virus

Squamous cells showing multinucleation, nuclear moulding and “ground-glass” appearance of nuclei.

SurePath™ - Herpes virus

SurePath™ - Herpes virus

Multinucleated cells with nuclear moulding, “ground glass” nuclear material and prominent nuclear inclusions.

ThinPrep - Actinomyces

ThinPrep - Actinomyces

Blue-staining, filamentous bacteria in dense clumps.

SurePath™ - Actinomyces

SurePath™ - Actinomyces

Dense clump of blue-staining
filamentous bacteria