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Details of Gene

Item Details
Gene/Locus name

CDKN2A (also called CDK4I,p16,INK4a,MTS1,CMM2,ARF,p19,p14,INK4,p16INK4a,p19Arf,p14ARF)

Long Name

cyclin dependent kinase inhibitor 2A (OMIM 600160)

Associated Disorders

OMIM 155601 : Melanoma, cutaneous malignant, 2
OMIM (n/a) : BAD DATA OMIM 606719 : Pancreatic cancer/melanoma syndrome
OMIM 155755 : Melanoma and neural system tumor syndrome

Interpretation / Comment

Laboratory methods do not necessarily identify all of the clinically significant variants in a gene. The failure to identify a variant does not necessarily mean that the gene is normal. Variants in a gene may cause more than one disease, and the identification of a clinically significant variant does not necessarily indicate the specific disease that the patient or relatives may be at risk of developing. Conversely, the disease/s associated with a gene might also be caused by mutations in other genes, and the failure to identify a clinically significant variant in one gene does not necessarily alter the clinical diagnosis or risk for relatives.

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