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Details of Gene

Item Details
Gene/Locus name

MET (also called HGFR,RCCP2,DFNB97)

Long Name

MET proto-oncogene, receptor tyrosine kinase (OMIM 164860)

Laboratories
Associated Disorders

OMIM 114550 : Hepatocellular carcinoma, childhood type, somatic
OMIM 607278 : Osteofibrous dysplasia, susceptibility to
OMIM 616705 : ?Deafness, autosomal recessive 97
OMIM 605074 : Renal cell carcinoma, papillary, 1, familial and somatic

Interpretation / Comment

Laboratory methods do not necessarily identify all of the clinically significant variants in a gene. The failure to identify a variant does not necessarily mean that the gene is normal. Variants in a gene may cause more than one disease, and the identification of a clinically significant variant does not necessarily indicate the specific disease that the patient or relatives may be at risk of developing. Conversely, the disease/s associated with a gene might also be caused by mutations in other genes, and the failure to identify a clinically significant variant in one gene does not necessarily alter the clinical diagnosis or risk for relatives.

HGNC Last Edit Date

6/12/2018