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Details of Gene

Item Details
Gene/Locus name

WFS1 (also called DIDMOAD,WFS)

Long Name

wolframin ER transmembrane glycoprotein (OMIM 606201)

Associated Disorders

OMIM 116400 : ?Cataract 41
OMIM 222300 : Wolfram syndrome 1
OMIM 614296 : Wolfram-like syndrome, autosomal dominant
OMIM 600965 : Deafness, autosomal dominant 6/14/38
OMIM 125853 : Diabetes mellitus, noninsulin-dependent, association with

Interpretation / Comment

Laboratory methods do not necessarily identify all of the clinically significant variants in a gene. The failure to identify a variant does not necessarily mean that the gene is normal. Variants in a gene may cause more than one disease, and the identification of a clinically significant variant does not necessarily indicate the specific disease that the patient or relatives may be at risk of developing. Conversely, the disease/s associated with a gene might also be caused by mutations in other genes, and the failure to identify a clinically significant variant in one gene does not necessarily alter the clinical diagnosis or risk for relatives.

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