Erythema multiforme

Keywords: Stevens-Johnson syndrome


Appropriate Tests


Review clinical findings. Full blood count, C-Reactive protein.

Skin biopsy with Immunofluorescence if diagnosis uncertain.

Stevens-Johnson syndrome is a term used to describe a severe form of erythema multiforme with mucosal lesions and a poor prognosis.


Drug reactions, especially;

  • Sulphonamides
  • Barbiturates
  • Phenytoin


Infections, especially;

  • Herpes simplex virus infection
  • Mycoplasma infection
  • Hepatitis B virus infection
  • Leprosy


Connective tissue diseases