Germ cell tumour

Key Information

Appropriate Tests


Common sites include testis, ovary, brain and mediastinum. Lesion biopsy.

Testicular biopsy as an intraoperative procedure should only be performed in specialist centres and if immediate orchidectomy is possible on diagnosis of malignancy.

Useful serum markers include Alpha-fetoprotein, Beta HCG quantitation, Lactate dehydrogenase isoenzymes.

Seminoma (dysgerminoma)


Embryonal carcinoma






Endodermal sinus tumour