Bordetella pertussis Ab

Keywords: Bordetella pertussis antibody, Bordetella pertussis serology, Pertussis antibody


5-10 mL blood in plain tube


EIA for IgA antibodies and sometimes other antibody classes to pertussis toxin.


Suspected pertussis early in the course of the illness, in conjunction with culture or nucleic acid detection after amplification.

Serum antibody test may be useful for retrospective diagnosis.


Serum IgA antibodies may not become positive until 2 weeks after commencement of symptoms.

IgA antibodies are not stimulated by vaccination, so a positive result in a vaccinated patient indicates past or current infection.

Only a minority of infants develop serum antibodies so the sensitivity of this test is poor.


Müller FC et al. J Clin Microbiol 1997; 35: 2435-2443.