Brucella Ab

Keywords: Brucella antibody, Brucella serology, Brucella abortus, Brucella suis, Brucella melitensis


5-10 mL blood in plain tube. Acute and convalescent (3-4 weeks) samples.


Bacterial agglutination, Coombs anti-human globulin test, CFT, EIA.


PUO with history of relevant animal exposure.


A bacterial agglutination titre of >160 suggests past or recent infection; a four-fold rise in titre between acute and convalescent samples is evidence of recent infection.

Blocking antibodies can lead to false negative results at low dilutions of serum.


Chu MC, Weyant RS. In: Murray PR et al, eds. Manual of Clinical Microbiology. 8th ed. Washington DC: ASM Press, 2003.