Haemoglobin urine


Freshly voided urine collected without preservative.


Spectroscopic examination or urinalysis to detect haem pigment.

Urine microscopy to exclude haematuria.

EPG or IFE to distinguish haemoglobin from myoglobin.

Reference Interval:

Not detected in normal urine.


History of red or dark urine; findings on FBC and blood film suggesting intravascular haemolysis; investigation of immediate haemolytic reaction during Blood transfusion.

See also Myoglobin urine.


Haemoglobinuria indicates intravascular haemolysis;

release of haemoglobin in amounts exceeding the binding capacity of haptoglobins; and

consequent glomerular filtration of haemoglobin and presence in urine.


Bain et al. Dacie and Lewis Practical Haematology. 11th Ed. 2012.