Oesophageal biopsy


Endoscopic biopsy specimen.


Separate containers should be used for each biopsy from different sites. 

Ideally the biopsy should be placed on to a small square of paper, orientated with the mucosa exposed and placed in formalin fixative. 

Light microscopy, histochemistry, immunohistochemistry.


Investigation of symptoms of reflux and dysphagia, acute and chronic oesophagitis, oesophageal polyp, Barrett's oesophagus, and surveillance of oesophageal dysplasia, malignancy.


Report by pathologist identifies nature of lesion sampled. 

In case of tumours type, grade and stage is reported.


Montgomery, E. Biopsy interpretation of Gastrointestinal Tract Mucosa. Vol 1 and 2. 2012 (2nd Ed) Lippincott, Williams and Wilkins.