The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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Key Information
Appropriate Tests
A mutation in the factor V coagulation molecule which renders it resistant to cleavage by activated protein C and leads to a condition referred to as activated protein C resistance.
It occurs in ~ 5% of the Australian population in the heterozygous form and is associated with an increased risk of venous thromboembolism.
The risk of arterial thrombosis does not appear to be increased.
Testing is indicated in patients who have had venous thromboembolism where investigation for an underlying cause is appropriate (see Thrombosis).
Testing is controversial and is not considered indicative in asymptomatic individuals unless the defect has been established in a first degree relative.
APC resistance (screening).
PCR for Factor V Leiden
See Molecular genetics - genetic disorders
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
The annual scientific meeting for the RCPA which covers the scientific disciplines of Anatomical, Chemical, Forensic, Genetic, General, Haematology, Immunopathology and Microbiology.
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