The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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Key information
Appropriate Tests
Rare B cell disorder characterised by production of truncated heavy chains of immunoglobulins, without associated light chain production. Three types based on the class of heavy chain produced:
See also Paraproteinaemia.
Diagnosis depends on demonstration of cells in affected tissue staining for heavy chain without any light chain components (lymph nodes, bone marrow, hepatosplenomegaly).
Protein electrophoresis, Paraprotein typing. Bone marrow biopsy (aspiration and trephine).
α Heavy chain disease
Malabsorption
γ Heavy chain disease
Uvular/palatal oedema
Hepatomegaly
Lymphadenopathy
μ Heavy chain disease
May be associated with Chronic lymphocytic leukaemia.
Splenomegaly
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
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