Keywords: Conn's syndrome

Key Information

Appropriate Tests


Patients usually present with hypertension and/or muscle weakness.

Electrolytes (hypokalaemia is usual, but a normal potassium does not exclude the diagnosis); Aldosterone / Renin ratio, Electrolytes urine.

If Aldosterone or aldosterone/renin ratio elevated, special studies are required - consult pathologist.


Hyporeninaemic hyperaldosteronism (Conn's syndrome).

Adrenal aldosterone secreting tumour (aldosteronoma)


Bilateral adrenal hyperplasia


Glucocorticoid suppressible

Aldosterone after 2 mg dexamethasone daily for 3 days.


Hyperreninaemic hyperaldosteronism.

Renal disease, especially


  • Renovascular

Bilateral renal vein Renin; Renin after captopril load.

  • Bartter’s syndrome

Not associated with hypertension.

  • Renal haemangiopericytoma


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