Hyperviscosity syndrome


Appropriate Tests


Initial clinical assessment; Full blood count, Blood film, Erythrocyte sedimentation rate.

Viscosity (plasma), occasionally of value. Viscosity whole blood is rarely of value.

Paraproteinaemia, especially

  • Plasma cell myeloma
  • Waldenström's macroglobulinaemia


Erythrocytosis (marked), especially

  • Polycythaemia vera


Leucocytosis (extreme), especially

  • Acute leukaemia
  • Chronic myeloid leukaemia


Rheumatoid arthritis


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