Appropriate Tests


Protein, Albumin.

Raised globulin suggests the presence of liver disease or other underlying disease process associated with reduced albumin synthesis.

Reduced albumin synthesis


  • Acute phase response


  • Chronic liver disease

See Cirrhosis and Autoimmune hepatitis under Hepatitis.

  • Severe/chronic illness


  • Severe Malnutrition


Increased albumin loss


  • Nephrotic syndrome


  • Protein losing enteropathy


Following plasma/blood loss, including


  • Post-operative


  • Extensive burns


  • Bullous skin lesions


Artefactual result

See Table 1.

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