The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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Causes
Appropriate Tests
Diagnosis and evaluation may involve assay of pituitary or target gland hormones.
Dynamic stimulation tests may assist to evaluate hormone reserves - consult pathologist.
Panhypopituitarism
Patients may have clinical or radiological evidence of a space occupying lesion in the pituitary fossa.
They may present initially with deficiency of a single hormone: Prolactin, Testosterone (in males), Luteinising hormone, Follicle stimulating hormone (in post-menopausal females), Thyroid stimulating hormone, Free T4, Cortisol, Growth hormone.
Non-functioning tumours
Functioning tumours
Alpha subunit - this may be the main secretory product of the tumour.
Hypothalamic disorders
See also Pituitary/hypothalamic disorders
Vascular disorders
Post-traumatic
Post-hypophysectomy
Post-irradiation
Septo-optic dysplasia
Granulomas
Empty sella syndrome
Genetic
Single hormone deficiency
May be the presenting feature of any cause of panhypopituitarism, however single hormone deficiency can occur and is usually genetic.
Growth hormone
Growth hormone stimulation test.
See Short stature
IGF-1.
Growth hormone resistance, rather than deficiency; growth hormone levels are usually high.
Thyroid stimulating hormone
See also Hypothyroidism.
Luteinising hormone, Follicle stimulating hormone
ACTH
See also Adrenocortical insufficiency.
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
The annual scientific meeting for the RCPA which covers the scientific disciplines of Anatomical, Chemical, Forensic, Genetic, General, Haematology, Immunopathology and Microbiology.
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