The main purpose of this Manual is to provide useful guidelines for the selection of pathology tests and to facilitate interpretation of results.
Contains a comprehensive listing of all genes from the Human Gene Nomenclature Committee (HGNC) database alongside laboratories and tests available in the country.
A manual for the process of macroscopic dissection in Anatomical Pathology laboratories.
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Review clinical findings, Full blood count, White cell count differential, Blood film.
Assessment of peripheral blood lymphocyte morphology assists in determining the aetiology of the lymphocytosis.
If lymphocytosis is persistent (>3 months) and the aetiology is uncertain, peripheral blood immunophenotyping by flow cytometry may be useful.
Syndromes characterised by lymphoid cells with atypical morphology (ie activated lymphocytes).
Other infections, especially
Characteristically lymphocytes are morphologically normal or show "reactive features".
Hyposplenism / Splenic atrophy or absence.
Associated features of hyposplenism in the peripheral blood film (Howell-Jolly bodies, target cells, acanthocytes, spherocytes, thrombocytosis).
See Splenic atrophy/absence
Transient lymphocytosis associated with physiological stress
Lymphoproliferative disorders, especially
Blood film morphology may be suggestive. Immunophenotyping of peripheral blood lymphoid cells has a role in sub-typing the lymphoid lineage, confirmation of clonality in B cell disorders and may identify a characteristic immunophenotype in some lymphoproliferative disorders.
Bain BJ. Blood cells: a practical guide. Fourth edition. Oxford: Blackwell Publishing, 2007
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The RCPA is the leading organisation representing Pathologists and Senior Scientists in Australasia.
Its mission is to train and support pathologists and senior scientists and to improve the use of pathology testing to achieve better healthcare.
The annual scientific meeting for the RCPA which covers the scientific disciplines of Anatomical, Chemical, Forensic, Genetic, General, Haematology, Immunopathology and Microbiology.
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