Mycoplasma infection


Appropriate Tests

Mycoplasma pneumoniae

Mycoplasma pneumoniae Ab titres; Cold agglutinins (not commonly performed); PCR (discuss with local pathologist).

Myringitis (bullous)


Acute bronchitis



MCS sputum to exclude other pathogens.



NAA on CSF may be negative and a high index of suspicion is required.

Vascular complications

  • Cold-related digital vasospasm


Autoimmune haemolysis

Full blood count, Blood film, Reticulocyte count; Cold agglutinins, Direct antiglobulin test.

Mycoplasma hominis


Non-gonococcal Urethritis

The role of M. hominis in disease of the genital tract infection is being questioned as the role of M. genitalium has become better appreciated

Wound infection

  • Sternotomy

Wound swab microscopy and culture with special request for mycoplasma culture.

Endocarditis (infective)

M. hominis should be considered in any culture-negative endocarditis.

Special blood culture - consult pathologist.



Mycoplasma genitalium


Non-gonococcal urethritis

M. genitalium is recognised as a cause of acute and chronic urethritis in males. Its role in disease of the female genital tract is yet to be clearly confirmed.

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