Myeloproliferative neoplasms
Keywords: MPN, Myeloproliferative disorders
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Key Information
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Appropriate Tests
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A group of related, clonal, stem cell disorders characterised by excessive production of erythrocytes and/or granulocytes and/or platelets, increased bone marrow fibrosis, splenomegaly and, often, hyperuricaemia.
They all have the potential for transformation to acute leukaemia. Please see individual clinical problem entries as listed below.
Myeloproliferative neoplasms (MPN) have been subclassified by the World Health Organization as follows:
See also Chronic leukaemia
Please see individual clinical problem entries as listed below:
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Chronic myeloid leukaemia
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Polycythaemia vera
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Essential thrombocythaemia (ET)
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Primary myelofibrosis
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Chronic eosinophilic leukaemia
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Chronic neutrophilic leukaemia
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Atypical chronic myeloid leukemia
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Chronic myeloproliferative disease - unclassifiable
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