Splenic atrophy/absence

Keywords: Splenectomy, Asplenia, Hyposplenism

Key Information

Appropriate Tests


Often detected on the basis of Full blood count and Blood film examination: red cell morphological changes, Thrombocytosis, Leucocytosis.





Congenital absence (asplenia)


Splenic atrophy/infarction

May be persistent splenomegaly, with haematological findings indicative of reduced splenic function.

  • Myeloproliferative neoplasms


  • Irradiation
  • Coeliac disease/other malabsorptive disorders


  • Dermatitis herpetiformis


  • Ulcerative colitis


  • Sickle cell anaemia

See Sickle cell disorders.



Increased susceptibility to infection, especially

See also Infection (increased susceptibility)

  • Streptococcus pneumoniae


  • Haemophilus influenzae type B

See Haemophilus influenzae infection.

  • Neisseria meningitidis

See Neisseria meningitidis (meningococcus)

  • Capnocytophaga canimorsus

See Wound infection

  • Cerebral malaria (babesiosus)


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