Testicular failure
Keywords: Gonodal hypofunction, Gondal hypofunction (male)
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Causes
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Appropriate Tests
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Clinical assessment includes testicular site and size, evidence of androgen deficiency and of hypothalamic or pituitary disorder.
Semen analysis - fertility, Follicle stimulating hormone, Luteinising hormone, Prolactin, Testosterone, Testicular biopsy is rarely appropriate.
See also Infertility (male and female)
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Hypogonadotrophic hypogonadism (hypothalamic/pituitary disorders)
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Gonadotrophin releasing hormone deficiency (Kallmann syndrome)
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Panhypopituitarism
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See under Hypopituitarism
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Prolactinoma
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Hereditary haemochromatosis
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Hypergonadotrophic hypogonadism (primary testicular disorders)
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Chromosome abnormalities
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Cytogenetics - constitutional.
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Cryptorchidism
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Bilateral anorchia
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Noonan syndrome
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Vanishing testis syndrome
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Acquired testicular failure
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Trauma - thermal/physical
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Usually eugonadotrophic.
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Cytotoxic drugs/irradiation
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History of Mumps, or other viral infection, associated with Orchitis.
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See under Muscular dystrophy
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Sperm Ab.
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