Appropriate Tests


Skin prick allergen testing or Allergen specific Immunoglobulin E to relevant antigen(s). Immunoglobulin E is not of clinical value.

May be associated with Anaphylaxis and Angioedema

See also Contact dermatitis

Stings and bites

See Insect sting sensitivity


  • Latex
  • Cosmetics

See Latex allergy

Blood components

See Blood transfusion - complications.

Infections, especially

  • Viral, in children

Spot/Allergy specific IgE may be of clinical use.

Food intolerance/allergy




Drug reactions, especially

  • Aspirin
  • NSAIDs
  • Penicillin, Amoxycilin
  • Sulphonamides



Full blood count; C-Reactive protein or Erythrocyte sedimentation rate; thyroid function tests, Thyroid Ab.

Skin biopsy, if indicated.

Skin prick allergen and testing for Allergen specific Immunoglobulin E are not of clinical value.

Underlying conditions

  • Connective tissue diseases
  • Vasculitis
  • Malignancy
  • Hepatitis B prodrome

See Hepatitis B virus infection.

  • Lymphoma (non-Hodgkin)
  • Hyperthyroidism / Hypothyroidism

Physical urticarias

  • Cold, heat, vibration  


See Cold related disorders - Cold Urticaria

Psychological stress


Mastocytosis (urticaria pigmentosa)


Recurrent skin prick testing


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